Anaerobic Microbiology Lead

PARIS, FRANCE          FULL-TIME

At Eligo, we are passionate about developing new drugs to address unmet medical needs!

Eligo is building a platform technology based on phage engineering to produce eligobiotics that can deliver therapeutic DNA and (re)program a wide range of bacterial species in-situ, both aerobic and anaerobic species. With such a capability, Eligo is poised to lead the new generation of precision microbiome engineering companies.

To be able to translate our research to the clinic, we need to design and engineer bacterial strains, therapeutic DNA circuits and phage genomes which will be used to produce our eligobiotics.

> We are therefore looking for an excellent microbiologist who has serious experience with anaerobic bacteria to lead our anaerobic lab, and excited to tackle the ambitious challenges of diving into phage genetics and engineering bacterial strains.

The ideal candidate is also interested in genetic engineering. He/she will work hand-in-hand with our synthetic biologists to engineer eligobiotic candidates to be used in our clinical trials.

Responsibilities

  • Lead the anaerobic lab set-up
  • Develop processes for multiple anaerobic species handling
  • Develop processes for phage discovery and production in anaerobic species
  • Genetic engineering of anaerobic species – method development and optimization 
  • Tune genetic expression on developed circuits for efficient function in target bacterial species
  • Engineer new DNA packaging and delivery systems based on engineered phages
  • Work hand-in-hand with other scientists to accelerate the process of eligobiotics engineering

 

Requirements

  • Ph.D. or equivalent at minimum
  • Demonstrated strong experience with anaerobic microbiology techniques
  • Phage and/or synthetic biology expertise a plus
  • Self-starter with strong attention to detail and accuracy and an ability to work independently to solve technical problems 
  • Ability to multi-task without compromising quality and accuracy 
  • Effective management of time and effort to meet deadlines 
  • Strong interactive skills and ability to work effectively in a team environment
  • Strong collaborative attitude essential